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Volume 7, Issue 2
DFT Study on the Mechanism of Water Oxidation Catalyzed by a Mononuclear Copper Complex

Zhi-Bo Yang, Xin Lu, Miao-Miao Li, Han-Xiao Guo & Si-Xiang Chen

Commun. Comput. Chem., 7 (2025), pp. 145-151.

Published online: 2025-06

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  • Abstract

This work employed DFT calculations to elucidate the mechanism of water oxidation reaction catalyzed by a mononuclear pyridine-based copper complex, which was reported to be a homogeneous water oxidation catalyst in a pH=11.84 buffer solution. The coordination of one water molecule with the ${\rm Cu}^{{\rm II}}$ center leads to the generation of the ${\rm Cu}^{{\rm II}}-{\rm OH}_2 (1-{\rm H}_2{\rm O}).$ The active species $({\rm Cu}^{{\rm IV}}={\rm O, 3})$ is generated after two subsequent proton-coupled electron transfer processes from $1-{\rm H}_2{\rm O}.$ $3$ triggers the O-O bond formation via water nucleophilic attack mechanism. The triplet ${\rm O}_2$ can be released after following two oxidation processes. The formation of the O-O bond is the rate-determining step for the catalytic cycle associated with a total barrier of 19.3 kcal/mol.

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@Article{CiCC-7-145, author = {Yang , Zhi-BoLu , XinLi , Miao-MiaoGuo , Han-Xiao and Chen , Si-Xiang}, title = {DFT Study on the Mechanism of Water Oxidation Catalyzed by a Mononuclear Copper Complex}, journal = {Communications in Computational Chemistry}, year = {2025}, volume = {7}, number = {2}, pages = {145--151}, abstract = {

This work employed DFT calculations to elucidate the mechanism of water oxidation reaction catalyzed by a mononuclear pyridine-based copper complex, which was reported to be a homogeneous water oxidation catalyst in a pH=11.84 buffer solution. The coordination of one water molecule with the ${\rm Cu}^{{\rm II}}$ center leads to the generation of the ${\rm Cu}^{{\rm II}}-{\rm OH}_2 (1-{\rm H}_2{\rm O}).$ The active species $({\rm Cu}^{{\rm IV}}={\rm O, 3})$ is generated after two subsequent proton-coupled electron transfer processes from $1-{\rm H}_2{\rm O}.$ $3$ triggers the O-O bond formation via water nucleophilic attack mechanism. The triplet ${\rm O}_2$ can be released after following two oxidation processes. The formation of the O-O bond is the rate-determining step for the catalytic cycle associated with a total barrier of 19.3 kcal/mol.

}, issn = {2617-8575}, doi = {https://doi.org/10.4208/cicc.2025.49.01}, url = {http://global-sci.org/intro/article_detail/cicc/24184.html} }
TY - JOUR T1 - DFT Study on the Mechanism of Water Oxidation Catalyzed by a Mononuclear Copper Complex AU - Yang , Zhi-Bo AU - Lu , Xin AU - Li , Miao-Miao AU - Guo , Han-Xiao AU - Chen , Si-Xiang JO - Communications in Computational Chemistry VL - 2 SP - 145 EP - 151 PY - 2025 DA - 2025/06 SN - 7 DO - http://doi.org/10.4208/cicc.2025.49.01 UR - https://global-sci.org/intro/article_detail/cicc/24184.html KW - water oxidation, density functional calculations KW - reaction mechanism, copper complex. AB -

This work employed DFT calculations to elucidate the mechanism of water oxidation reaction catalyzed by a mononuclear pyridine-based copper complex, which was reported to be a homogeneous water oxidation catalyst in a pH=11.84 buffer solution. The coordination of one water molecule with the ${\rm Cu}^{{\rm II}}$ center leads to the generation of the ${\rm Cu}^{{\rm II}}-{\rm OH}_2 (1-{\rm H}_2{\rm O}).$ The active species $({\rm Cu}^{{\rm IV}}={\rm O, 3})$ is generated after two subsequent proton-coupled electron transfer processes from $1-{\rm H}_2{\rm O}.$ $3$ triggers the O-O bond formation via water nucleophilic attack mechanism. The triplet ${\rm O}_2$ can be released after following two oxidation processes. The formation of the O-O bond is the rate-determining step for the catalytic cycle associated with a total barrier of 19.3 kcal/mol.

Yang , Zhi-BoLu , XinLi , Miao-MiaoGuo , Han-Xiao and Chen , Si-Xiang. (2025). DFT Study on the Mechanism of Water Oxidation Catalyzed by a Mononuclear Copper Complex. Communications in Computational Chemistry. 7 (2). 145-151. doi:10.4208/cicc.2025.49.01
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